Leishmania mexicana is a protist that causes disease in humans by infecting and living within our immune cells. This panels shows its lifecycle in the insect vector.

An over-expressed GFP-protein fusion is sorted to the lysosome for recycling, making this organelle fluoresce green. Hence we can follow the behaviour of this organelle, that has a curious tubular morphology, through cell division in the insect stage (promastigote).

Waller, R.F. and McConville, M.J. (2002) Developmental changes in lysosome morphology and function in Leishmania parasites. Int. J. Parasitol. 32: 1435-45